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Pablo Lapuerta Selected Research

(2S,3R,4R,5S,6R)- 2- (4- chloro- 3- (4- ethoxybenzyl)phenyl)- 6- (methylthio)tetrahydro- 2H- pyran- 3,4,5- triol

12/2021Efficacy and safety of sotagliflozin in patients with type 2 diabetes and severe renal impairment.
1/2021Sotagliflozin in Patients with Diabetes and Chronic Kidney Disease.
1/2021Improvement in Patient-Reported Outcomes in Adults with Type 1 Diabetes Treated with Sotagliflozin plus Insulin Versus Insulin Alone.
1/2021Sotagliflozin in Patients with Diabetes and Recent Worsening Heart Failure.
11/2020Sotagliflozin added to optimized insulin therapy leads to HbA1c reduction without weight gain in adults with type 1 diabetes: A pooled analysis of inTandem1 and inTandem2.
11/2020Diabetic Ketoacidosis and Related Events With Sotagliflozin Added to Insulin in Adults With Type 1 Diabetes: A Pooled Analysis of the inTandem 1 and 2 Studies.
11/2019Insights Into Patients' Experience With Type 1 Diabetes: Exit Interviews From Phase III Studies of Sotagliflozin.
9/2018HbA1c and Hypoglycemia Reductions at 24 and 52 Weeks With Sotagliflozin in Combination With Insulin in Adults With Type 1 Diabetes: The European inTandem2 Study.
9/2018Sotagliflozin in Combination With Optimized Insulin Therapy in Adults With Type 1 Diabetes: The North American inTandem1 Study.
12/2017Effects of Sotagliflozin Added to Insulin in Patients with Type 1 Diabetes.
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Pablo Lapuerta Research Topics

Disease

20Carcinoid Tumor (Carcinoid)
01/2022 - 10/2014
14Diarrhea
01/2022 - 11/2010
12Hypertension (High Blood Pressure)
10/2018 - 02/2002
11Type 2 Diabetes Mellitus (MODY)
12/2021 - 08/2004
8Type 1 Diabetes Mellitus (Autoimmune Diabetes)
01/2021 - 07/2015
7Neuroendocrine Tumors (Neuroendocrine Tumor)
01/2020 - 10/2014
6Diabetic Ketoacidosis (Ketoacidosis, Diabetic)
01/2021 - 12/2017
6Heart Failure
01/2021 - 06/2002
5Body Weight (Weight, Body)
12/2021 - 07/2013
5Hypoglycemia (Reactive Hypoglycemia)
01/2021 - 07/2015
3Infections
01/2021 - 03/2015
3Cardiovascular Diseases (Cardiovascular Disease)
01/2021 - 11/2003
3Weight Loss (Weight Reduction)
09/2018 - 07/2015
3Stroke (Strokes)
04/2016 - 11/2003
3Chronic Kidney Failure (Chronic Renal Failure)
11/2006 - 08/2004
2Chronic Renal Insufficiency
12/2021 - 01/2021
2Weight Gain
11/2020 - 01/2018
2Neoplasms (Cancer)
01/2020 - 01/2020
2Nausea
01/2018 - 01/2017
2Flushing
01/2018 - 04/2015
2Hemorrhage
09/2016 - 11/2010
2Coronary Artery Disease (Coronary Atherosclerosis)
04/2016 - 11/2010
2Alzheimer Disease (Alzheimer's Disease)
01/2011 - 01/2002
2Diabetic Nephropathies (Diabetic Nephropathy)
11/2006 - 08/2004
1Hypotension (Low Blood Pressure)
01/2021
1Albuminuria
01/2021
1Acute Kidney Injury (Acute Renal Failure)
01/2021
1Hyperglycemia
11/2019
1Carcinoid Heart Disease
01/2019
1Chest Pain (Chest Pains)
10/2018
1Abdominal Pain (Pain, Abdominal)
01/2018
1Acute Coronary Syndrome
09/2016
1Hyperlipidemias (Hyperlipidemia)
04/2016
1Peripheral Arterial Disease
04/2016
1Heart Valve Diseases (Valvular Heart Disease)
04/2015
1Urinary Tract Infections (Urinary Tract Infection)
03/2015
1Obesity
12/2007
1Diabetes Mellitus
08/2005
1Cerebrovascular Disorders (Cerebrovascular Occlusion)
01/2003
1Coronary Disease (Coronary Heart Disease)
01/2003

Drug/Important Bio-Agent (IBA)

15telotristat ethylIBA
01/2022 - 01/2017
15(2S,3R,4R,5S,6R)- 2- (4- chloro- 3- (4- ethoxybenzyl)phenyl)- 6- (methylthio)tetrahydro- 2H- pyran- 3,4,5- triolIBA
12/2021 - 07/2013
11Somatostatin (Somatotropin Release-Inhibiting Factor)IBA
01/2022 - 01/2017
8IrbesartanFDA LinkGeneric
10/2009 - 08/2004
7Insulin (Novolin)FDA Link
01/2021 - 07/2015
7Serotonin (5 Hydroxytryptamine)IBA
01/2020 - 10/2014
7Tryptophan HydroxylaseIBA
11/2019 - 01/2016
5Glucose (Dextrose)FDA LinkGeneric
12/2021 - 07/2013
5Sodium-Glucose Transport ProteinsIBA
01/2021 - 03/2015
5Hydrochlorothiazide (Esidrix)FDA LinkGeneric
10/2009 - 12/2006
5Antihypertensive Agents (Antihypertensives)IBA
12/2007 - 01/2003
4telotristatIBA
01/2018 - 10/2014
3Sodium-Glucose Transporter 2 InhibitorsIBA
01/2021 - 07/2015
3Glycated Hemoglobin (Glycosylated Hemoglobin)IBA
01/2021 - 07/2013
3Octreotide (Sandostatin)FDA LinkGeneric
10/2018 - 10/2014
3CreatinineIBA
11/2006 - 08/2004
2SodiumIBA
12/2021 - 01/2015
2Sodium-Glucose Transporter 1IBA
09/2018 - 09/2018
2Pharmaceutical PreparationsIBA
11/2017 - 06/2002
22'- deoxythymidylyl- (3'- 5')- 2'- deoxyadenosine (d(AT))IBA
09/2016 - 04/2016
2Omeprazole (Prilosec)FDA LinkGeneric
09/2016 - 11/2010
2Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
04/2016 - 11/2010
2Metformin (Glucophage)FDA LinkGeneric
03/2015 - 07/2013
2Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
08/2005 - 08/2004
2omapatrilatIBA
08/2004 - 06/2002
1Tryptophan (L-Tryptophan)FDA Link
01/2020
1KetonesIBA
11/2019
1Cholinergic Antagonists (Anticholinergics)IBA
01/2019
1AtropineFDA LinkGeneric
01/2019
1DiphenoxylateFDA LinkGeneric
01/2019
1Loperamide (Imodium)FDA LinkGeneric
01/2019
1Hydroxyindoleacetic AcidIBA
01/2018
1Blood Glucose (Blood Sugar)IBA
12/2017
1Acetic Acid (Vinegar)FDA LinkGeneric
01/2017
15-hydroxyindoleIBA
01/2017
1TransferasesIBA
01/2017
1AcidsIBA
10/2014
1Biomarkers (Surrogate Marker)IBA
01/2011
1Donepezil (Aricept)FDA LinkGeneric
01/2011
1Clopidogrel (Plavix)FDA Link
11/2010
1Angiotensin Receptor AntagonistsIBA
05/2009
1ThiazidesIBA
05/2009
1DiureticsIBA
08/2005
1Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
08/2005
1Cardiac GlycosidesIBA
08/2005
1Indicators and Reagents (Reagents)IBA
08/2005
1Spironolactone (Aldactone)FDA LinkGeneric
08/2005
1Calcium Channel Blockers (Blockers, Calcium Channel)IBA
08/2004
1Angiotensin II Type 2 Receptor BlockersIBA
08/2004
11,4-dihydropyridine (dihydropyridine)IBA
08/2004
1cyclo(Arg-Pro) (CI 4)IBA
05/2004
1Vasopeptidase InhibitorsIBA
06/2002
1Lisinopril (Prinivil)FDA LinkGeneric
06/2002

Therapy/Procedure

21Therapeutics
01/2021 - 02/2002
3Glycemic Control
12/2017 - 07/2013
2Percutaneous Coronary Intervention
09/2016 - 04/2016
1Injections
12/2017
1Drug Tapering
07/2015
1Drug Therapy (Chemotherapy)
05/2004
1Ambulatory Care (Outpatient Care)
11/2003